Rh-catalyzed transannulation of pyridotriazoles with alkynes and nitriles

Abstract

(Chemical Equation Presented) Changing the rings: A variety of N-fused pyrrolo- and imidazopyridines can be readily formed by a direct Rh-catalyzed transannulation of pyridotriazoles with alkynes and nitriles, respectively (see scheme). Substituted pyridotriazoles can also serve as stable precursors for Rh carbenoids, the preparation of which does not require special precautions or slow-addition techniques. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.