Lupus pathogenesis: Role of IgE autoantibodies

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Abstract

IgE is commonly known for its role in the Th2 responses, protection against helminth parasites and pathogenesis of allergy. A recent report shows that IgE autoantibodies to dsDNA plays a major role in the pathogenesis of lupus nephritis by exacerbating the interferon-alpha; responses in plasmacytoid dendritic cells.

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Bayry, J. (2016, March 1). Lupus pathogenesis: Role of IgE autoantibodies. Cell Research. Nature Publishing Group. https://doi.org/10.1038/cr.2016.12

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