Secondary metabolites of Volvariella bombycina and their inhibitory effects on melanogenesis

Abstract

Four compounds were isolated from the culture broth of Volvariella bombycina and they were identified as ergosta-4,6,8(14), 22-tetraene-3-one (1), ergosterol peroxide (2), indole-3-carboxaldehyde (3), and indazole (4) by interpretation of spectroscopic data. Among them, compound 2 exhibited melanogenesis inhibitory effect in cultured B16 mouse melanoma cells. ©The Korean Society for Microbiology and Biotechnology.