Controlled conjugation of nanoparticles with single stranded DNA

  • Maeda Y
  • Nakamura T
  • Uchimura K
  • et al.
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Abstract

The controlled conjugation of Au nanoparticles using single-stranded DNA has been achieved by Watson–Crick base pairing interaction and a biotin-streptavidin reaction. Observation by atomic force microscopy have confirmed the one-to-one binding of Au nanoparticles to plasmid DNA. The results suggest that this method could be utilized to achieve nanoscale arrangements in a wide range of applications.

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Maeda, Y., Nakamura, T., Uchimura, K., Matsumoto, T., Tabata, H., & Kawai, T. (1999). Controlled conjugation of nanoparticles with single stranded DNA. Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures Processing, Measurement, and Phenomena, 17(2), 494–496. https://doi.org/10.1116/1.590583

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