Acute and long-term outcome of cryoablation therapy of typical atrioventricular nodal reentrant tachycardia

Abstract

AimsThe purpose of this study was to evaluate the safety and efficacy of cryoablation in a large series of patients with typical (slow-fast) atrioventricular nodal reentrant tachycardia (AVNRT).Methods and resultsBetween 2003 and 2007, 312 patients with typical AVNRT- median age of 53 years (range 10-92), 200 women (64)- underwent cryoablation, using exclusively a 6 mm tip catheter tip. Acute success was achieved in 309 of 312 patients (99). The overall recurrence rate was 18 of 309 (5.8) during a mean follow-up of 673 ± 381 days. Sixteen of these patients (89) were successfully reablated. The recurrence rate was 9 in patients with residual dual atrioventricular (AV) nodal pathway post-ablation compared with 4 in those with complete elimination of slow pathway conduction (P = 0.05). No patient developed permanent AV block.ConclusionCryoablation of AVNRT can be achieved with a high acute success rate and a reasonable recurrence rate at long-term follow-up. Complete abolition of slow pathway conduction seems to predict better late outcome.