SARS-CoV-2 detection in cerebrospinal fluid in a pediatric patient. Case report

Abstract

The SARS-CoV-2 virus, responsible for the COVID-19 pandemic, is an emerging infectious agent. The knowledge of both its infectivity mechanisms and the possible complications and specific treatments is the subject of constant research. To understand the involvement of the central nervous system in children, the behavior of this germ is studied based on the neuroinvasive properties of certain respiratory viruses, the neurological damage caused by other coronaviruses, and the clinical manifestations in adults with COVID-19. We describe the clinical case of a 2-month-old patient who consulted for fever without a focus with detection of SARSCoV-2 by reverse transcription polymerase chain reaction in nasopharyngeal secretions and cerebrospinal fluid. The infant presented good evolution, with resolution of the fever and without compromise or neurological manifestations.