Toxicological studies of the effects of ethanolic extracts of avocado (Persea Americana Mill.) seed flour on experimental animals

Abstract

Ethanolic extract of Avocado (Persea americana) seed flour was assessed for histopathologic and haematological parameters of Albino rats treated with varying dosage (250, 500 and 1000mg/kg) of the extracts. The haematological parameters were RBC, PCV, Hb, WBC, PLT, MCV, MCH and MCHC with range of values 7.01 to 7.32x106mm3, 43.40 to 46.80%, 14.86 to 16.12g/dl, 8.94 to 9.26x103mm3, 89.40 to 94.60x103/mm3, 61.93 to 63.97f1, 21.06 to 22.02pg and 33.17 to 34.73g/dl respectively. The seed extracts did not have adverse effects on the hematological parameters. Conclusively, these seeds should be harnessed and utilized for food and feed production.