Background: Cardiac tumours are rare, and clinical manifestations depend on the anatomical location. Symptoms can be the result of cardiac outflow anomalies, constitutional features such as fever, loss of weight, and/or paraneoplastic manifestations such as arthritis. To date, there has only been one other case report in the literature of cardiac sarcoma presenting as paraneoplastic arthropathy. Case presentation: A 52-year-old woman presented with acute onset corticosteroid-resistant inflammatory polyarthralgia, clubbing and a systolic murmur. Transthoracic echocardiogram revealed a dilated left atrium with an echogenic mass and brain magnetic resonance imaging revealed multiple embolic infarcts. Histopathology following emergency resection showed a Grade 3 left atrial intimal sarcoma. The polyarthralgia and clubbing resolved soon after tumour removal. The patient went on to receive chemotherapy and remains in remission. Conclusions: This case highlights the rare paraneoplastic association of cardiac sarcoma and arthropathy.
CITATION STYLE
Ung, N., Gunasingam, C., Cai, K., Manolios, N., Bayly, A., Dinh, P., … Wong, P. (2023). Cardiac sarcoma presenting as paraneoplastic arthritis and clubbing: a case report and literature review. BMC Rheumatology, 7(1). https://doi.org/10.1186/s41927-023-00350-x
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