Effect of different analgesic treatments on the pulmonary function in elderly hip fracture patients: A prospective study

Abstract

Background: To investigate the effect of different analgesic methods on lungs in elderly patients with hip fractures. Methods: A prospective study was conducted on 78 elderly hip fracture patients undergoing spinal anesthesia for surgery, where 3 analgesic methods were used: postoperative Patient-controlled intravenous analgesia pump (PCIA) (group I), pre and postoperative PCIA (group II), and preoperative fascia iliaca compartment block (FICB) + postoperative PCIA (group III). The following indicators were monitored at admission (T1), on the day of surgery before anesthesia (T2), and 7 days after surgery (T3): heart rate (HR), respiratory rate (RR), forced expiratory volume during the first second, arterial partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2), C-reactive protein (CRP), and interleukin 6 (IL-6). Pulmonary complications such as pulmonary atelectasis and respiratory insufficiency were analyzed. Results: The HR, RR, forced expiratory volume during the first second, PaO2, PaCO2, IL-6, and CRP levels at T1 after fracture did not significantly differ among the 3 groups (P >.05). After different analgesic treatments post-admission, all indicators at T2 were significantly higher in group I than in groups II and III (P.05). At T3, there were no significant differences in RR, HR, PaO2, PaCO2, and CRP levels among the groups (P >.05), but IL-6 levels at T3 were significantly higher in group I than in groups II and III (P