Bioactive secondary metabolites with unique aromatic and heterocyclic structures obtained from terrestrial actinomycetes species

Abstract

Natural products from actinomycetes are important and valuable sources for drug discovery and the development of biological tools. The present review describes our recent study on the isolation of new naturalproducts mainly possessing heterocyclic and aromatic ring structures with biological effects on cancer-relatedcellular pathways such as tumor necrosis factor-α-related apoptosis-inducing ligand (TRAIL) and Wnt signaling.