Synthesis and anti-bacterial activity of some azo compounds

Abstract

Some azo compounds were prepared by the reaction of 4-amino benzamide with benzoyl chloride forming N-benzoyl-4-amino benzamide, the later was diazotized to give N-benzoyl-4-((substituted phenyl)diazenyl)benzamide (1-6). The compounds were characterized by F.T-IR, 1H-NMR and 13C-NMR. The azo derivatives (1-6) were tested for their antibacterial activity against (S. aureus, S. epidermidis, E. coli and P. aeruginosa) by using disc diffusion method. The minimum inhibitory concentrations (MICs) of the compounds also calculated by agar streak dilution method. The azo derivatives show moderate activity against the used bacteria.