Effect of Hippophae Rhamnoides Leaf Extract against Dengue Virus Infection in U937 Cells

Abstract

Hippophae rhamnoides (Seabuckthorn) (Family: Elaegnaceae), a medicinal plant from Himalayas, traditionally used for health promotion. The study has been designed to investigate the effect of Sea buckthorn leaf alcoholic extract and other well-known medicinal plants, in Dengue infected U-937 cells (Human Monocytic cell line), as monocytes are the host cells for Dengue virus. Significantly high anti-dengue activity of Seabuckthorn was observed indicating it as a potential candidate for management of Dengue infection.