The Use of Melastoma malabatricum and Manihot esculenta extract as natural anthelmintic on the Performance of Kacang goat

Abstract

This study was carried out to evaluate anthelmintic activity of the combination Melastoma malabatrucum and Cassava (Manihot esculenta) leaves extract on the performance of Kacang goat The first experiment was conducted to examine the efication of thus extract on larva development assay and adult motility assay. In the second experiment, twenty Kacang goat were distributed into four groups according to a Completely Randomized Design namelly P1= 75% Melastoma malabatricum extract + 25% Manihot esculenta extract. P2= 50% Melastoma malabatricum extract + 50% Manihot esculenta extract P3= 25% Melastoma malabatricum extract + 75% Manihot esculenta extract P4= : Single dose Ivermectin as positif control. Extract All experimental goats were dewormed with Albendazole and treated prophylactically with a broad-spectrum antibiotic before the experiment. Goat were infected orally with 200 infective Haemonchus contortus larvae (L3). Result indicated that Melastoma malabatrucum leaves extract inhibited larvae development assay by 77% compared with 71.5% on Cassava (Manihot esculenta) leaves extract. For the mean of adult motility assay increase in the concentration of extract from 3.125-50 mg/mL. Our finding also found the was significant different (P<0.05) on dry matter intake and there no significant different on live weight, no mortality was found during experimental periods.