Differences in hemagglutination inhibition activity against bovine rotavirus and hen newcastle disease virus based on the subunits in hen egg white ovomucin

Abstract

The hemagglutination inhibition (HI) activity of ovomucin (OM) subunits, and the effects of alkylation before and after reduction and protease treatments on the HI activity of OM to bovine rotavirus (RV) and hen newcastlc disease virus (NDV) were investigated. The appearance of the HI activity of OM against RV was accomplished by a macromolecule composed of α- and β-subunits, while that against NDV required the β-subunit moiety only. © 1996, Taylor & Francis Group, LLC. All rights reserved.