Association between volume status as assessed by bioelectrical impedance analysis and echocardiographic parameters in peritoneal dialysis patients

Abstract

Aims: Fluid overload is one of the major problems causing severe complications in dialysis patients and the assessment of volume status is important for these patients. The aim of the study was to evaluate the relationship of fluid overload measured by bioimpedance analysis (BIA) with different echocardiographic parameters in peritoneal dialysis (PD) patients. Methods: In this study, transthoracic echocardiography and BIA were performed on 35 PD patients. Patients were divided into two groups: overhydrated (OH) (OH ≥1.1) and non-OH <1.1. This study assessed the differences in echocardiographic parameters between two groups and the association between BIA parameters and echocardiographic parameters including right heart indices. Results: A total of 35 dialysis patients (21 males) were enrolled in the study. Based on OH, 21 patients (60%) with OH ≥1.1 (lt) were considered OH and 14 patients (40%) were considered non-OH. There was no significant difference in respect to gender, age, hypertension, diabetes and dialysis vintage between two groups. Among the left heart echocardiographic parameters, left ventricular (LV) mass index (LVMI) was significantly higher in the OH group (119.0±40.3 vs. 239.4±37.4 g/m2, p=0.046). There was no significant difference with regard to other left and right ventricular echocardiographic parameters. Among various BIA parameters, we investigated OH, OH/extracellular water (ECW), ECW/total body water ratios and their correlations with echocardiographic parameters. We did not find any significant correlation between BIA parameters and echocardiographic findings. Conclusions: The present study demonstrated the association between the hydration status and LVMI. We conclude that avoiding hypervolemia should be an important clinical goal in the follow-up of PD patients to prevent the progression of LV hypertrophy.