Chemical microarrays to identify ligands that bind pathogenic cells

Abstract

Tryptamine trial. Chemical microarrays have been used to identify ligands that recognize the surface of a variety of pathogenic organisms. In each case, the highest affinity ligand is tryptamine, which is shown to recognize cell surfaces when multivalently displayed on a microarray surface or on a water-soluble polymer. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.