“Multiplexing” cells of the visual cortex and the timing enigma of the binding problem

Abstract

In this opinion essay, I address the perennial binding problem, that is to say of how independently processed visual attributes such as form, colour and motion are brought together to give us a unified and holistic picture of the visual world. A solution to this central issue in neurobiology remains as elusive as ever. No one knows today how it is implemented. The issue is not a new one and, though discussed most commonly in the context of the visual brain, it is not unique to it either. Karl Lashley summarized it well years ago when he wrote that a critical problem for brain studies is to understand how “the specialized areas of the cerebral cortex interact to provide the integration evident in thought and behaviour” (Lashley, 1931).