Abstract
A novel retrosynthetic approach to 3,5-diaryl-2-pyrazolines is provided by a three-component, one-pot reaction initiated by a palladium/copper- catalyzed cross-coupling (see scheme). The initially formed enone cyclocondenses in situ with the hydrazine to furnish the heterocycle. EWG = electron-withdrawing group.
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APA
Müller, T. J. J., Ansorge, M., & Aktah, D. (2000). An unexpected coupling-isomerization sequence as an entry to novel three-component-pyrazoline syntheses. Angewandte Chemie - International Edition, 39(7), 1253–1256. https://doi.org/10.1002/(SICI)1521-3773(20000403)39:7<1253::AID-ANIE1253>3.0.CO;2-X
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