Invasive group A streptococcal infections, clinical manifestations and their predictors, Montreal, 1995-2001

42Citations
Citations of this article
33Readers
Mendeley users who have this article in their library.

Abstract

We identified 306 invasive group A streptococcal infections (IGASI) by passive population-based surveillance in Montreal, Canada, from 1995 to 2001. The average yearly reported incidence was 2.4 per 100,000 persons, with a 14% death rate. Among clinical manifestations, incidence of pneumonia increased from 0.06 per 100,000 in 1995 to 0.50 per 100,000 in 2000. Over a span of 7 years, the odds of developing pneumonia increased (odds ratio [OR] = 1.21, 95% confidence interval [Cl] 1.0-1.5), while they decreased for soft-tissue infections (OR = 0.86, 95% Cl 0.7-1.0). Serotypes M1 and M3 accounted for 30% of IGASI. However, neither serotype was significantly associated with specific clinical manifestations, which suggests that manifestation development among IGASI might be attributable to host or environmental factors rather than the pathogen. In our study, these factors included age, gender, underlying medical conditions, and living environment, yet none explained temporal changes in risk for pneumonia and soft-tissue infections.

Cite

CITATION STYLE

APA

Hollm-Delgado, M. G., Allard, R., & Pilon, P. A. (2005). Invasive group A streptococcal infections, clinical manifestations and their predictors, Montreal, 1995-2001. Emerging Infectious Diseases, 11(1), 77–82. https://doi.org/10.3201/eid1101.030651

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free