High-flow vs conventional oxygen therapies for acute cardiogenic pulmonary edema following hip fractures and surgery in elderly patients

Abstract

Purpose: This prospective, randomized controlled study aimed to compare the effects of high-flow oxygen therapy and conventional oxygen therapy in the treatment of acute cardiogenic pulmonary edema following hip fractures and surgery in elderly patients. Methods: From February 2018 to October 2023, 124 patients diagnosed with acute cardiogenic pulmonary edema following hip fractures and surgery were randomly assigned to the high-flow oxygen therapy group (n=62) or conventional oxygen therapy group (n=65). Partial pressure of oxygen (PO2) and blood oxygen saturation (SPO2) were assessed 60 minutes after the treatments. A P value <0.05 was considered statistically significant. Results: There were significant differences in PO2 (66.2 ± 3.3 mmHg vs 62.1 ± 3.4 mmHg, P<0.05) and SPO2 (97.8 ± 2.1 mmHg vs 94.2 ± 1.7 mmHg, P<0.05) between the groups. Conclusion: In the treatment of elderly patients with ACPE following hip fractures and surgery, high-flow oxygen therapy may be performed to improve ventilation when acute cardiogenic pulmonary edema does not significantly improve within 15 minutes of conventional oxygen therapy.