Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

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Abstract

Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P =.0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.

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Thompson, G. R., Blair, J. E., Wang, S., Bercovitch, R., Bolaris, M., Van Den Akker, D., … Johnson, R. (2017). Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis. Clinical Infectious Diseases, 65(2), 338–341. https://doi.org/10.1093/cid/cix318

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