Acute arterial and venous thrombosis in patients infected with COVID-19

Abstract

Background: There are recognized complications in patients infected by COVID-19 and thrombotic processes are closely related to infection. Objective: To describe the factors associated with increased risk in thrombotic events in COVID-19. Material and methods: Case-control study to identify factors associated with thrombotic processes in patients with COVID-19. Descriptive, comparative and inferential statistics were used, as well as logistic regression.The value of p <0.05 was determined as statistically significant and the statistical program IBM SPSS V.25 was used. Results: 15 cases of acute thrombosis were assesed, 17.5% were arterial and 8.8% were venous, 66.7% (n = 10) were men.Therapeutic anticoagulation and surgical procedures were neccesary. There was an association as a risk factor the fact of presenting some comorbidity (p = 0.005), and prolonged aPTT (p = 0.10), as well as abnormalities in the D-dimer. Conclusions: Infected patients suffers from hypercoagulability and confers a high risk of thrombosis. Significant elevation of D-dimer may be one of the markers of inflammation. The condition of presenting COVID-19 is not a contraindication for any revascularization procedure, which encourages us to improve our diagnostic and therapeutic behavior in patients with COVID-19 infection.