Journal Article

Lethal Capecitabine Toxicity in Patients With Complete Dihydropyrimidine Dehydrogenase Deficiency Due to Ultra-Rare DPYD Variants

  • van Kuilenburg A
  • Pleunis-van Empel M
  • Brouwer R
  • et al.
JCO Precision Oncology (2024) (8)
DOI: 10.1200/po.23.00599
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Abstract

A DPD deficiency should be considered in case of severe toxicity even in the absence of common risk variants in DPYD.

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van Kuilenburg, A. B. P., Pleunis-van Empel, M. C. H., Brouwer, R. B., Sijben, A. E. J., Knapen, D. G., Oude Munnink, T. H., … Niezen-Koning, K. E. (2024). Lethal Capecitabine Toxicity in Patients With Complete Dihydropyrimidine Dehydrogenase Deficiency Due to Ultra-Rare DPYD Variants. JCO Precision Oncology, (8). https://doi.org/10.1200/po.23.00599

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