Anesthetic considerations in the management of mucormycosis

Abstract

Mucormycosis or zygomycosis is a well described but a complex disease which appears unseemingly benign but is fatally malignant in its behaviour. Mucormycosis causes severe tissue destruction by endothelial invasion. Our pateint was 65 year old lady with palatal mucormycosis with uncotrolled diabetes who was treated successfully with systemic amphotericin B and surgical debridement which is the main stay of treatment of mucormycosis. Systemic amphotericin B has a lots of side effects like fever, shivering, hypotension, hypoxia, arrhythmia and mainly nephrotoxicity. Our aim is to highlight the need for early diagnosis and surgical debridement of necrotic tissues while keeping in mind the toxic effects of systemic amphotericin B and its interaction with anaesthetic agents.