Rotating-frame intermolecular double-quantum spin-lattice relaxation T 1ρ,DQC-weighted magnetic resonance imaging

Abstract

In this study, spin-locking techniques were added as a part of intermolecular multiple-quantum experiments, thereby introducing the concept of rotating-frame intermolecular double-quantum spin-lattice relaxation, T 1ρ, DQC. A novel magnetic resonance imaging methodology based on intermolecular multiple-quantum coherences is demonstrated on a 7.05-T microimaging scanner. The results clearly reveal that the intermolecular double-quantum coherence T1ρ, DQC-weighted imaging technique provides an alternative contrast mechanism to conventional imaging. © 2005 Wiley-Liss, Inc.