Optical coherence tomography: A novel modality for scrotal imaging

Abstract

Background: For patients with nonobstructive azoospermia, sperm retrieval rates remain modest. We describe the use of optical coherence tomography to improve retrieval rates and to decrease tissue destruction. Methods: Four patients underwent diagnostic testicular biopsy and imaging with the Niris optical coherence tomography de - vice. We performed a descriptive comparison between optic al coherence tomographic images and conventional histology. Results: The measured seminiferous tubule diameter differed by 16 μm between comparative imaging from optical coherence tomography and conventional histology using hematoxylin and eosin staining. Conclusion: We illustrate the usefulness of optical coherence tomography in the setting of testicular biopsy and the management of nonobstructive azoospermia. © 2009 Canadian Urological Association.