Montmorillonite K-10 clay as an efficient reusable heterogeneous catalyst for the solvent-free microwave mediated synthesis of 5-substituted 1H-tetrazoles

Abstract

Various 5-substituted 1H-tetrazole derivatives were synthesized in a simple and environmentally benign method from the reaction of aryl and benzyl nitriles with sodium azide in solvent-free media using montmorillonite K-10 clay as solid recyclable heterogeneous acidic catalyst and microwave irradiation in good yields and short reaction times. Copyright © 2005 KCSNET.