Fitting fixed-and random-effects meta-analysis models using structural equation modeling with the sem and gsem commands

Abstract

In this article, we demonstrate how to fit fixed-and random-effects meta-analysis, meta-regression, and multivariate outcome meta-analysis models under the structural equation modeling framework using the sem and gsem commands. While all of these models can be fit using existing user-written commands, formulating the models in the structural equation modeling framework provides deeper insight into how they work. Further, the heterogeneity test for metaregression and multivariate meta-analysis is readily available from this output.