Designing a Probabilistic Index for Improving the Diagnostic Accuracy of Troponin in Patients With Acute Coronary Events

Abstract

The positive endpoint was defined as either positive evidence in coronary angiography, ST segment elevation on ECG or sudden cardiac arrest within 7 days of presentation. A set of clinical and paraclinical variables were evaluated in patients, including age, gender, race/ethnicity, chest pain, duration of pain, reproducible chest pain, sweating, history of coronary artery disease (CAD), dyspnea, hypertension, diabetes mellitus, family history of CAD, history of congestive heart failure, current/recent smoking, systolic blood pressure, diastolic blood pressure, BMI, increased cholesterol, T wave inversion, ST depression, normal ECG and Q waves.