Electrochemical Detection of Dopamine at a Novel Poly(2,4,6-trihydroxybenzaldehyde) Film Modified Electrode

Abstract

In this study, a novel electrodeposition of poly(2,4,6-trihydroxybenzaldehyde) on bare glassy carbon electrode for dopamine detection was reported. 2,4,6-trihydroxybenzaldehyde and the electrodeposited poly(2,4,6-trihydroxybenzaldehyde) were characterized using Fourier transform-infrared spectroscopy, UV-visible spectroscopy, and scanning electron microscopy. The bare electrode modified with the optimum amount of 2,4,6-trihydroxybenzaldehyde (PTGCE) was used for dopamine electroanalysis. The linear dynamic range and the limit of detection of DA at PTGCE were 0.70-19.48 μM and 19.48–53.30 μM, and 0.64 μM, respectively. The modified electrode showed outstanding discriminatory dopamine detection in the presence of uric acid and ascorbic acid due to a dopamine-uric acid and a dopamine-ascorbic acid peak-to-peak separation of 160 mV and 200 mV, respectively. The proposed sensor showed considerable reproducibility of dopamine current response and excellent % dopamine recovery of 99.70 % from the real sample solution.