Gamma interferon modifies CD4+ subset expression in murine candidiasis

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Abstract

A single injection of monoclonal antibody to gamma interferon administered in conjunction with a live Candida albicans yeast cell vaccine resulted in the detection of nonprotective Th2 rather than protective Th1 responses and altered the early expression of interleukin 4 and gamma interferon mRNA in CD4+ cells.

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Romani, L., Cenci, E., Mencacci, A., Spaccapelo, R., Grohmann, U., Puccetti, P., & Bistoni, F. (1992). Gamma interferon modifies CD4+ subset expression in murine candidiasis. Infection and Immunity. https://doi.org/10.1128/iai.60.11.4950-4952.1992

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