Cytotoxic activity of methanol extraction of Avicennia marina and taurin in the HeLa cancer cells

Abstract

The aim of study was to determine any anticancer potential from Avicennia marina leaf extract compare to taurine on cytotoxic and anti-proliferation activities against HeLa cervical cancer cell line by using the MTT method (3-(4, 5-dimethylthiazol-2-yl))-2, 5-diphenyltetrazolium bromide). The results indicated that methanol extraction of A. marina leaf as well as taurine did have cytotoxic and anti-proliferation effects on HeLa cell line with IC50 values of 321 ppm and 603 ppm 1000 ppm. While the doubling time value for anti-proliferation of A. marina leaf methanol extraction and taurine showed higher values than the control group (72.19 hours).