Abstract
Indole and carbazole derivatives were designed as non-competitive antagonists of the GluK2 receptor. The synthesized compounds were found to interact with the transduction domain of the receptor. The binding pocket is situated within one receptor subunit.
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Kaczor, A. A., Pihlaja, K., Sinkkonen, J., Wiinamäki, K., Kronbach, C., Unverferth, K., … Matosiuk, D. (2014). Synthesis and molecular docking of indole and carbazole derivatives with potential pharmacological activity. Heterocyclic Communications, 20(2), 103–109. https://doi.org/10.1515/hc-2014-0006
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