Lavendomycin, a new antibiotic I. taxonomy, isolation and characterization

Abstract

Lavendomycin, a new basic peptide antibiotic containing novel amino acids, has been isolated from the culture broth of a streptomyces designated as Streptomyces lavendulae subsp. brasilicus. The antibiotic obtained as colorless crystals (C29H50N10O8, MW 666) is active against Gram-positive bacteria in vitro and in vivo, however, inactive against Gramnegative bacteria and fungi. An acute toxicity of the antibiotic in mice was LD50 >2 g/kg by subcutaneous injection. © 1985, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.