Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants

Gemma Texidó; Heinz Jacobs; Myriam Meiering; Ralf Kühn; Jürgen Roes; Werner Müller; Susan Gilfillan; Hiroshi Fujiwara; Hitoshi Kikutani; Nobuaki Yoshida; Ryuichi Amakawa; Christophe Benoist; Diane Mathis; Tadamitsu Kishimoto; Tak W. Mak; Klaus Rajewsky

Journal ArticleOPEN ACCESS

Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants

European Journal of Immunology (1996) 26(8) 1966-1969

DOI: 10.1002/eji.1830260843

13Citations

13Readers

Get full text

Abstract

We show through sequence analysis of rearranged immunoglobulin variable (Ig-V) region genes from memory B cells of mouse mutants generated by gene targeting that terminal deoxynucleotidyl transferase, CD23, interleukin-4, IgD and CD30 are dispensable for somatic hypermutation.

Author supplied keywords

Cite

CITATION STYLE

APA

Texidó, G., Jacobs, H., Meiering, M., Kühn, R., Roes, J., Müller, W., … Rajewsky, K. (1996). Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants. European Journal of Immunology, 26(8), 1966–1969. https://doi.org/10.1002/eji.1830260843

Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants

Abstract

Author supplied keywords

Cite

Register to see more suggestions