Assessment of Public Interest in the Use of Munjaro for Weight Loss in Ha'il City Community, KSA

Abstract

Background: Obesity has become a critical public health challenge in Saudi Arabia, driving growing interest in pharmacological weight-management options, including off-label use of GLP-1-based therapies such as tirzepatide (Mounjaro). This study aimed to assess public knowledge, perceptions and interest in Mounjaro among adults in Ha’il, focusing on awareness sources, perceived effectiveness, safety concerns, eligibility criteria and understanding of FDA approval status. Methods: A cross-sectional electronic survey was distributed via social media platforms between December 2024 and February 2025, yielding responses from approximately 200 participants. Data were analysed using SPSS version 27, employing descriptive statistics and Chi-square tests with a significance threshold of p < .05. Results: The findings revealed high general awareness of Mounjaro (93%), with healthcare staff, family and social media serving as the primary information sources. Despite broad awareness, detailed knowledge remained limited, as 48% reported low and 25% no knowledge of the medication. Most participants perceived Mounjaro as effective for weight loss (92.5%) and were familiar with common side effects such as nausea and vomiting. Education level and knowledge significantly influenced the likelihood of consulting a doctor, while gender differences showed higher awareness among females. A strong majority (88%) expressed a need for increased public education. Conclusion: These results highlight widespread interest but insufficient understanding of Mounjaro, emphasizing the need for targeted awareness campaigns and evidence-based health communication strategies.