This study analyzes the use of sodium nitroprusside (SN) as an option to reduce blood pressure (BP) below 180/105 mmHg during the management of acute ischemic stroke (AIS) in patients submitted to intravenous thrombolysis. Method: The sample was composed by 60 patients who had AIS and were submitted to intravenous rtPA, split in two groups: half in the control group (CG) with BP < 180/105 mmHg and half in SN group with BP > 180/105 mmHg. Outcome variables were any hemorrhagic transformation (HT); the presence of symptomatic HT, National Institute of Health Stroke Scale (NIHSS) after 24 hours of treatment; the independence on discharge and death until three months after stroke onset. Results: There were no statistical differences between both groups to any of the outcome variables analyzed. Conclusion: The SN might be safe for BP control during thrombolysis to AIS.
CITATION STYLE
Koslyk, J. L., Ducci, R. D., Nóvak, E. M., Zétola, V. F., & Lange, M. C. (2015). Sodium nitroprusside: Low price and safe drug to control BP during thrombolysis in AIS. Arquivos de Neuro-Psiquiatria, 73(9), 755–758. https://doi.org/10.1590/0004-282X20150104
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