Seroprevalence of NMO-IgG antibody in Brazilian patients with neuromyelitis optica

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Abstract

Objective: To determine the seroprevalence of neuromyelitis optica antibody (NMO)-IgG in Brazilian patients with clinical diagnosis of relapsing neuromyelitis optica, also known as Devic's disease. Method: We determined NMO-IgG titers in 28 patients (25 of them females) that fulfilled the 1999 NMO diagnostic criteria proposed by Wingerchuk et al. Results: NMO-IgG was detected in 18 NMO patients (64.3%). Conclusion: Our results showed that seroprevalence of NMO-IgG in Brazilian NMO patients was similar to the observed in other studies.

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Adoni, T., Lino, A. M. M., Marchiori, P. E., Kok, F., & Callegaro, D. (2008). Seroprevalence of NMO-IgG antibody in Brazilian patients with neuromyelitis optica. Arquivos de Neuro-Psiquiatria, 66(2 B), 295–297. https://doi.org/10.1590/S0004-282X2008000300001

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