Bioactive constituents of Garcinia porrecta and G. parvifolia grown in Indonesia

Abstract

A new xanthone, porxanthone A (1) and one porlanosterol (2) were isolated; and three known xanthones, dulxanthone E (3), dulxanthone F (4), dulxanthone G (5) from G. porrecta, whereas two known xanthones, parvixanthone A (6) and rubraxanthone (7), were isolated from G. parvifolia. The structures of these compounds were determined by spectroscopic data analysis. The results of cytotoxicity evaluation showed that (3), (4), (5), (6), (7) were inhibitory to L1210 cells, with IC 50 values in the range of 3 to 8 μg mL -1. © 2006 Asian Network for Scientific Information.