Clonal spread of carbapenem-resistant OXA-23-positive Acinetobacter baumannii in a Bulgarian university hospital

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Abstract

From October 1999 to September 2006, 29 carbapenem-resistant isolates of Acinetobacter baumannii were collected consecutively from patients hospitalized in different wards of the University Hospital in Pleven, Bulgaria. The blaOXA-23 gene, associated with the upstream-located IS Aba1, was identified as the mechanism responsible for carbapenem resistance in all isolates. The isolates belonged to two different clonal groups, indicating a sustained hospital outbreak. This study demonstrates both the epidemic potential of carbapenem-resistant A. baumannii and its longevity in the hospital environment. © 2008 European Society of Clinical Microbiology and Infectious Diseases.

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Stoeva, T., Higgins, P. G., Bojkova, K., & Seifert, H. (2008). Clonal spread of carbapenem-resistant OXA-23-positive Acinetobacter baumannii in a Bulgarian university hospital. Clinical Microbiology and Infection, 14(7), 723–727. https://doi.org/10.1111/j.1469-0691.2008.02018.x

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