Microevolution of Burkholderia pseudomallei during an acute infection

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Abstract

We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for the rapid in vivo diversification of B. pseudomallei after inoculation and systemic spread. Copyright © 2014 Limmathurotsakul et al.

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Limmathurotsakul, D., Holden, M. T. G., Coupland, P., Price, E. P., Chantratita, N., Wuthiekanun, V., … Peacock, S. J. (2014). Microevolution of Burkholderia pseudomallei during an acute infection. Journal of Clinical Microbiology. American Society for Microbiology. https://doi.org/10.1128/JCM.01219-14

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