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20S ways to apoptosis

Nature Chemical Biology
DOI: 10.1038/nchembio0908-528
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Abstract

Chemical inhibitors of the proteasome have received substantial attention owing to the success of bortezomib in the treatment of multiple myeloma. A recent whole-cell screen identified the proteasome inhibitor argyrin A and suggests a new role for p27Kip-1 in regulating apoptosis. © 2008 Nature Publishing Group.

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McConkey, D. J. (2008). 20S ways to apoptosis. Nature Chemical Biology. Nature Publishing Group. https://doi.org/10.1038/nchembio0908-528

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