B complex vitamins for analgesic therapy

  • Gazoni F
  • Malezan W
  • Santos F
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BACKGROUND AND OBJECTIVES: The B complex vi-tamins have been used as single therapy or combined to other drugs, such as anti-inflammatory drugs, in different clinical situ-ations, such as degenerative spinal diseases, rheumatologic dise-ases, polyneuropathies and in different postoperative situations. This study aimed at identifying in the scientific literature most recent evidences of the use of B complex vitamins as analgesic therapy and at describing clinical situations where their analgesic action could be observed. " pyri-doxine " and " cyanocobalamin " . Among 40 studies found, we have selected just musculoskeletal and neuropathic pain trials with humans, and where B complex vitamins were used as anal-gesic agents. From these, 13 studies were selected for meeting inclusion criteria. In all of them, B complex vitamins played ro-les in analgesia, even when in single therapy. B complex vitamins had also anti-inflammatory and anti-pruritus action, in addition to improving functionality. CONCLUSION: Existing studies, although scarce and hete-rogeneous, have shown that B complex vitamins have analgesic effect. They are considered safe and have low cost and have sho-wn to be a good option as adjuvant analgesic therapy.




Gazoni, F. M., Malezan, W. R., & Santos, F. C. (2016). B complex vitamins for analgesic therapy. Revista Dor, 17(1). https://doi.org/10.5935/1806-0013.20160013

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