Mechanism of histone survival during transcription by RNA polymerase II

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Abstract

Transcription of eukaryotic genes by RNA polymerase II is typically accompanied by minimal exchange of histones H3/H4 carrying various covalent modifications. In vitro studies suggest that histone survival is accompanied by the formation of a small transient DNA loop on the surface of the histone octamer including a molecule of transcribing enzyme. © 2010 Landes Bioscience.

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Kulaeva, O. I., & Studitsky, V. M. (2010). Mechanism of histone survival during transcription by RNA polymerase II. Transcription, 1(2), 85–88. https://doi.org/10.4161/trns.1.2.12519

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