Journal ArticleOPEN ACCESS

Effects of F171 mutations in the 6'-N-acetyltransferase type Ib [AAC(6')-Ib] enzyme on susceptibility to aminoglycosides

Antimicrobial Agents and Chemotherapy (1999) 43(11) 2811-2812
DOI: 10.1128/aac.43.11.2811
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Abstract

Substitutions at position F171 of 6'-N-acetyltransferase type Ib cause variable loss of aminoglycoside resistance, indicating that this residue plays an important role in the structure and/or function of the enzyme.

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Chavideh, R., Sholly, S., Panaite, D., & Tolmasky, M. E. (1999). Effects of F171 mutations in the 6’-N-acetyltransferase type Ib [AAC(6’)-Ib] enzyme on susceptibility to aminoglycosides. Antimicrobial Agents and Chemotherapy, 43(11), 2811–2812. https://doi.org/10.1128/aac.43.11.2811

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