No evidence for association to the G72/G30 locus in an independent sample of schizophrenia families

Abstract

Multiple studies report positive associations between SNPs at the G72/G30 locus and schizophrenia, although published findings do not consistently implicate the same alleles. The authors investigated association at this locus for previously reported SNPs using a family-based sample. No association was demonstrated, despite prior evidence for linkage in this sample to chromosome 13q32. The authors concluded that the G72/G30 locus is unlikely to contribute to schizophrenia susceptibility in this sample. © 2005 Nature Publishing Group. All rights reserved.