A TB model with infectivity in latent period and imperfect treatment

Abstract

An epidemiological model of TB with infectivity in latent period and imperfect treatment is introduced. As presented, sustained oscillations are not possible and the endemic proportions either approach the disease-free equilibrium or an endemic equilibrium. The expanded model that stratified the infectious individuals according to their time-since-infection is also carried out. The global asymptotic stability of the infection-free state is established as well as local asymptotic stability of the endemic equilibrium. At the end, numerical simulations are presented to illustrate the results. Copyright © 2012 Juan Wang et al.