Journal ArticleOPEN ACCESS

Production of hydroxlated flavonoids with cytochrome P450 BM3 variant F87V and their antioxidative activities

Bioscience, Biotechnology and Biochemistry (2013) 77(6) 1340-1343
DOI: 10.1271/bbb.130148
9Citations
Citations of this article
23Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

A variant of P450 BM3 with an F87V substitution [P450 BM3 (F87V)] is a substrate-promiscuous cytochrome P450 monooxygenase. We investigated the bioconversion of various flavonoids (favanones, chalcone, and isoflavone) by using recombinant Escherichia coli cells, which expressed the gene coding for P450 BM3 (F87V), to give their corresponding hydroxylated products. Potent antioxidative activities were observed in some of the products.

Author supplied keywords

Cite

CITATION STYLE

APA

Kitamura, E., Otomatsu, T., Maeda, C., Aoki, Y., Ota, C., Misawa, N., & Shindo, K. (2013). Production of hydroxlated flavonoids with cytochrome P450 BM3 variant F87V and their antioxidative activities. Bioscience, Biotechnology and Biochemistry, 77(6), 1340–1343. https://doi.org/10.1271/bbb.130148

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free