Regiospecific preparation of 1,4,5-trisubstituted pyrazoles from 2-(1H-1,2,3-benzotriazol-1-yl)-3-(4-aryl)-2-propenals

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Abstract

Treatment of α-benzotriazolyl-α,β-unsaturated aldehydes with monosubstituted hydrazines followed by alkylation at the 4-position of the pyrazoline ring and elimination of the benzotriazole group affords 1,4,5-trisubstituted pyrazoles in overall yields of 52-79%. ©ARKAT USA, Inc.

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APA

Katritzky, A. R., Vakulenko, A. V., Akue-Gedu, R., Gromova, A. V., Witek, R., & Rogers, J. W. (2007). Regiospecific preparation of 1,4,5-trisubstituted pyrazoles from 2-(1H-1,2,3-benzotriazol-1-yl)-3-(4-aryl)-2-propenals. Arkivoc, 2007(1), 9–21. https://doi.org/10.3998/ark.5550190.0008.102

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