Multidrug-resistant Shigella infections in patients with diarrhea, Cambodia, 2014–2015

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Abstract

We observed multidrug resistance in 10 (91%) of 11 Shigella isolates from a diarrheal surveillance study in Cambodia. One isolate was resistant to fluoroquinolones and cephalosporins and showed decreased susceptibility to azithromycin. We found mutations in gyrA, parC, β-lactamase, and mphA genes. Multidrug resistance increases concern about shigellosis treatment options.

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Poramathikul, K., Bodhidatta, L., Chiek, S., Oransathid, W., Ruekit, S., Nobthai, P., … Swierczewski, B. (2016). Multidrug-resistant Shigella infections in patients with diarrhea, Cambodia, 2014–2015. Emerging Infectious Diseases, 22(9), 1640–1643. https://doi.org/10.3201/eid2209.152058

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